Dr. Leonardo D. Borregales is a urologic oncologist and an Assistant Professor at Columbia University’s Division of Urology at Mount Sinai Medical Center.

Dr. Borregales earned his medical degree from Universidad Central de Venezuela, Luis Razetti School of Medicine in Caracas, Venezuela. He completed his postdoctoral fellowship training at UT – MD Anderson Cancer Center in Houston, TX. Following his postdoctoral fellowship training, he completed his residency training at UTHealth, McGovern Medical School, where he was honored for his academic research productivity on behalf of the Department of Urology. Following his residency, Dr. Borregales completed his fellowship training in Urologic Oncology at Weill Cornell Medicine/New York Presbyterian.

Dr. Borregales aims to provide the most comprehensive and innovative care for patients with prostate, bladder, kidney, ureteral, and testicular cancer. His goal is to deliver personalized patient care by combining his passion for surgery, research, and innovation. He has authored numerous publications in leading peer-reviewed journals and presented in national and international meetings on topics that include improving the management of localized and advanced kidney cancer, access to chemotherapy to treat bladder cancer, prostate cancer biopsy, active surveillance, and focal therapy.

Dr. Borregales is an associate member of the European Association of Urology – YAU Kidney Cancer Research working group, a member of the American Urological Association, National Hispanic Medical Association, Sexual Medicine Society of North America, National Postdoctoral Association, American Society of Clinical Oncology, and Sociedad Venezolana de Urologia.

Dr. Borregales is fluent in English and Spanish.

Areas of Clinical Interest:

Kidney cancer, bladder and upper tract urothelial cancer, prostate cancer, penile and testicular cancer

*This physician is employed by Mount Sinai Medical Center

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Borregales, L. D., Venkat, S., Posada Calderon, L., Lewicki, P., Flynn, T., Faltas, B. M., Molina, A. M., Golombos, D. M., O’Malley, P., & Scherr, D. S. (2023). A Pilot Study on Hyperthermic Intraperitoneal Chemotherapy after Radical or Partial Cystectomy with Pelvic Lymph Node Dissection for High-risk Muscle-invasive Bladder Cancer. European urology, S0302-2838(23)02900-7. Advance online publication.

Carbonara, U., Amparore, D., Borregales, L. D., Caliò, A., Ciccarese, C., Diana, P., Erdem, S., Marandino, L., Marchioni, M., Muselaers, C. H. J., Palumbo, C., Pavan, N., Pecoraro, A., Roussel, E., Warren, H., Wu, Z. J., Campi, R., & Bertolo, R. (2023). Single-port robotic partial nephrectomy: impact on perioperative outcomes and hospital stay. Therapeutic advances in urology, 15, 17562872231172834.

Marchioni, M., Amparore, D., Pecoraro, A., Bertolo, R., Campi, R., & EAU Young Academic Urologists (YAU) Renal Cancer Working Group (2023). Morbidity and mortality of metastasectomy for renal cell carcinoma: is centralization of care the way forward?. Minerva urology and nephrology, 75(3), 413–416.

Wu, Z., Amparore, D., Campi, R., Erdem, S., Bertolo, R., & EAU Young Academic Urologists (YAU) – Renal Cancer Working Group (2023). Prevention of the “cheese-cutter effect” during renorrhaphy after partial nephrectomy: by modifying available techniques or by just omitting cortical renorrhaphy?. Minerva urology and nephrology, 75(3), 410–412.

Warren, H., Palumbo, C., Caliò, A., Tran, M. G. B., Campi, R., & European Association of Urology (EAU) Young Academic Urologists (YAU) Renal Cancer Working Group (2023). Oncocytoma on renal mass biopsy: why is surgery even performed?. World journal of urology, 41(6), 1709–1710.

Marandino, L., Ciccarese, C., Francolini, G., Amparore, D., Campi, R., & EAU Young Academic Urologists (YAU) Renal Cancer working group (2023). The role of stereotactic ablative body radiotherapy in renal cell carcinoma: focus on oligometastatic and oligoprogressive disease. Minerva urology and nephrology, 75(2), 260–264.

Borregales, L. D., Tzeng, M., Ramaswamy, A., Gu, X., Davuluri, M., Nagar, H., & Hu, J. C. (2023). Prostate cancer grade migration and facility-level treatment trends for grade group 1 disease. JNCI cancer spectrum, 7(2), pkad018.

Muselaers, S., Amparore, D., Bertolo, R., Diana, P., Erdem, S., Marandino, L., Carbonara, U., Borregales, L. D., Pavan, N., Pecoraro, A., Roussel, E., Pecoraro, A., Campi, R., & Marchioni, M. (2022). Optimizing postoperative follow-up in RCC patients: why does it always have to be black and white?. Minerva urology and nephrology, 74(6), 822–824.

Bertolo, R., Amparore, D., Diana, P., Erdem, S., Marandino, L., Carbonara, U., Borregales, L. D., Muselaers, S., Pavan, N., Pecoraro, A., Roussel, E., Pecoraro, A., Marchioni, M., Campi, R., & EAU Young Academic Urologists (YAU) Renal Cancer working group (2022). Cryoablation of small renal masses in patients with solitary kidneys: worth crossing the road for?. Minerva urology and nephrology, 74(6), 794–798.

Brant, A., Campi, R., Carrion, D. M., Esperto, F., Sze, C., Johnson, J. P., Hu, J. C., & Borregales, L. D. (2022). Findings from an international survey of urology trainee experience with prostate biopsy. BJU international, 10.1111/bju.15935. Advance online publication.

Borregales, L. D., DeMeo, G., Gu, X., Cheng, E., Dudley, V., Schaeffer, E. M., Nagar, H., Carlsson, S., Vickers, A., & Hu, J. C. (2022). Response to Takahashi. Journal of the National Cancer Institute, 114(11), 1557–1558.

Dhanji, S., Borregales, L. D., Janzen, N. K., Godoy, G., Fuller, M. Y., & Au, J. K. (2022). Infant prostatic Rhabdomyosarcoma: A diagnostic and therapeutic challenge. Urology case reports, 43, 102116.

Basourakos, S. P., Al Hussein Al Awamlh, B., Borregales, L. D., Abrahimi, P., Sedrakyan, A., Shoag, J. E., & Hu, J. C. (2022). A comparative population-based analysis of peritoneal carcinomatosis in patients undergoing robotic-assisted and open radical cystectomy. International urology and nephrology, 54(7), 1513–1519.

Borregales, L. D., DeMeo, G., Gu, X., Cheng, E., Dudley, V., Schaeffer, E. M., Nagar, H., Carlsson, S., Vickers, A., & Hu, J. C. (2022). Grade Migration of Prostate Cancer in the United States During the Last Decade. Journal of the National Cancer Institute, 114(7), 1012–1019.

Venkat, S., Lewicki, P. J., Khan, A. I., Gaffney, C., Borregales, L., & Scherr, D. S. (2022). Sociodemographic Disparities in Access to Chemotherapy for Bladder Cancer. Clinical genitourinary cancer, 20(2), e140–e150.

Venkat, S., Khan, A. I., Lewicki, P. J., Borregales, L., & Scherr, D. S. (2022). Novel nomograms to predict muscle invasion and lymph node metastasis in upper tract urothelial carcinoma. Urologic oncology, 40(3), 108.e11–108.e17.

Gregg, J. R., Borregales, L. D., Choi, H., Lozano, M., McRae, S. E., Venkatesan, A. M., Davis, J. W., Nogueras-Gonzalez, G. M., Pisters, L. L., & Ward, J. F. (2021). Prospective trial of regional (hockey-stick) prostate cryoablation: oncologic and quality of life outcomes. World journal of urology, 39(9), 3259–3264.

Borregales, L. D., Saavedra-Belaunde, J., Wang, R., & Clavell-Hernández, J. (2020). Novel protective penile collar following inflatable penile prosthesis placement: The “Wang Collar”. Asian journal of andrology, 22(5), 481–484.

Borregales, L. D., Adibi, M., Thomas, A. Z., Reis, R. B., Chery, L. J., Devine, C. E., Wang, X., Potretzke, A. M., Potretzke, T., Figenshau, R. S., Bauman, T. M., Aboshady, Y. I., Abel, E. J., Matin, S. F., Karam, J. A., & Wood, C. G. (2021). Predicting Adherent Perinephric Fat Using Preoperative Clinical and Radiological Factors in Patients Undergoing Partial Nephrectomy. European urology focus, 7(2), 397–403.

Yu, K. J., Keskin, S. K., Meissner, M. A., Petros, F. G., Wang, X., Borregales, L. D., Gu, C., Tamboli, P., Matin, S. F., Wood, C. G., & Karam, J. A. (2018). Renal cell carcinoma and pathologic nodal disease: Implications for American Joint Committee on Cancer staging. Cancer, 124(20), 4023–4031.

Hutchinson, R., Rew, C., Chen, G., Woldu, S., Krabbe, L. M., Meissner, M., Sheth, K., Singla, N., Shakir, N., Master, V. A., Karam, J. A., Matin, S. F., Borregales, L. D., Wood, C., Masterson, T., Thompson, R. H., Boorjian, S. A., Leibovich, B. C., Abel, E. J., Bagrodia, A., … Margulis, V. (2018). The Adverse Survival Implications of Bland Thrombus in Renal Cell Carcinoma With Venous Tumor Thrombus. Urology, 115, 119–124.

Chéry, L., Borregales, L. D., Fellman, B., Urbauer, D. L., Garg, N., Parker, N., Katz, M. H. G., Wood, C. G., & Karam, J. A. (2017). The Effects of Neoadjuvant Axitinib on Anthropometric Parameters in Patients With Locally Advanced Non-metastatic Renal Cell Carcinoma. Urology, 108, 114–121.

Abel, E. J., Spiess, P. E., Margulis, V., Master, V. A., Mann, M., Zargar-Shoshtari, K., Borregales, L. D., Sexton, W. J., Patil, D., Matin, S. F., Wood, C. G., & Karam, J. A. (2017). Cytoreductive Nephrectomy for Renal Cell Carcinoma with Venous Tumor Thrombus. The Journal of urology, 198(2), 281–288.

Lucchesi, F. R., Reis, R. B., Faria, E. F., Machado, R. D., Rossini, R. R., Borregales, L. D., Silva, G. E., & Muglia, V. F. (2017). Incremental value of MRI for preoperative penile cancer staging. Journal of magnetic resonance imaging : JMRI, 45(1), 118–124.

Thomas, A. Z., Adibi, M., Slack, R. S., Borregales, L. D., Merrill, M. M., Tamboli, P., Sircar, K., Jonasch, E., Tannir, N. M., Matin, S. F., Wood, C. G., & Karam, J. A. (2016). The Role of Metastasectomy in Patients with Renal Cell Carcinoma with Sarcomatoid Dedifferentiation: A Matched Controlled Analysis. The Journal of urology, 196(3), 678–684.

Borregales, L. D., Adibi, M., Thomas, A. Z., Wood, C. G., & Karam, J. A. (2016). The role of neoadjuvant therapy in the management of locally advanced renal cell carcinoma. Therapeutic advances in urology, 8(2), 130–141.

Thomas, A. Z., Adibi, M., Borregales, L. D., Karam, J. A., & Wood, C. G. (2015). Cytoreductive surgery in the era of targeted molecular therapy. Translational andrology and urology, 4(3), 301–309.

Borregales, L. D., Kim, D. Y., Staller, A. L., Qiao, W., Thomas, A. Z., Adibi, M., Tamboli, P., Sircar, K., Jonasch, E., Tannir, N. M., Matin, S. F., Wood, C. G., & Karam, J. A. (2016). Prognosticators and outcomes of patients with renal cell carcinoma and adjacent organ invasion treated with radical nephrectomy. Urologic oncology, 34(5), 237.e19–237.e2.37E26.

Adibi, M., Thomas, A. Z., Borregales, L. D., Matin, S. F., Wood, C. G., & Karam, J. A. (2015). Surgical considerations for patients with metastatic renal cell carcinoma. Urologic oncology, 33(12), 528–537.

Adibi, M., Kenney, P. A., Thomas, A. Z., Borregales, L. D., Nogueras-González, G. M., Wang, X., Devine, C. E., Karam, J. A., & Wood, C. G. (2016). Prediction of Pulmonary Metastasis in Renal Cell Carcinoma Patients with Indeterminate Pulmonary Nodules. European urology, 69(2), 352–360.

Thomas, A. Z., Adibi, M., Borregales, L. D., Wood, C. G., & Karam, J. A. (2015). Role of metastasectomy in metastatic renal cell carcinoma. Current opinion in urology, 25(5), 381–389.

Adibi, M., Thomas, A. Z., Borregales, L. D., Merrill, M. M., Slack, R. S., Chen, H. C., Sircar, K., Murugan, P., Tamboli, P., Jonasch, E., Tannir, N. M., Matin, S. F., Wood, C. G., & Karam, J. A. (2015). Percentage of sarcomatoid component as a prognostic indicator for survival in renal cell carcinoma with sarcomatoid dedifferentiation. Urologic oncology, 33(10), 427.e17–427.e4.27E23.

Thomas, A. Z., Adibi, M., Borregales, L. D., Hoang, L. N., Tamboli, P., Jonasch, E., Tannir, N. M., Matin, S. F., Wood, C. G., & Karam, J. A. (2015). Surgical Management of Local Retroperitoneal Recurrence of Renal Cell Carcinoma after Radical Nephrectomy. The Journal of urology, 194(2), 316–322.

Borregales, L. D., Berg, W. T., Tal, O., Wambi, C., Kaufman, S., Gaya, J. M., Urzúa, C., & Badani, K. K. (2013). ‘Trifecta’ after radical prostatectomy: is there a standard definition?. BJU international, 112(1), 60–67.