Respiratory

Ages Eligible for Study: 18 Years and older   (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Patients who need the fresh biopsy must also submit whole blood for ctDNA testing Patients must have pathologically proven non-small cell lung cancer (all histologic types) confirmed by tumor biopsy and/or…

Ages Eligible for Study: Child, Adult, Older Adult Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Participants must have been assigned to S1800D by the Southwest Oncology Group (SWOG) Statistics and Data Management Center (SDMC). Assignment to S1800D is determined by the LUNGMAP or S1400 protocol Participants must have measurable or…

Ages Eligible for Study: 18 Years and older (Adult, Older Adult) Genders Eligible for Study: Both Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Patients must have undergone complete surgical resection of their stage IB (>= 4 cm), II, or IIIA NSCLC per American Joint Committee on Cancer (AJCC) 7th edition and have had negative margins;…

Ages Eligible for Study: 18 Years and older   (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Histologically or cytologically documented Stage I to II NSCLC, with clinical Stage I/II lymph node-negative (T1 to T3N0M0) disease and planned to receive definitive treatment with SBRT. Patients may be medically…

Ages Eligible for Study: 18 Years and older   (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: REGISTRATION STEP 1 Participants must have pathologic (cytological or histological) proof of non-small cell lung cancer (NSCLC) Participants must have stage III NSCLC with Zubrod performance status of 2 or stage…

Ages Eligible for Study: 18 Years and older   (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Histologically or cytologically confirmed diagnosis of NSCLC with KRAS G12C mutation. Candidacy to receive treatment with docetaxel. Exclusion Criteria: Prior treatment with an agent targeting KRAS G12C (e.g., AMG 510). Active…

Ages Eligible for Study: 18 Years and older   (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Patients must have histologically or cytologically confirmed stage IV non-squamous non-small cell lung cancer (NSCLC) (includes M1a, M1b, and M1c stage disease, American Joint Committee on Cancer [AJCC] 8th edition). Patients…

Ages Eligible for Study: 18 Years and older Genders Eligible for Study: Both Accepts Healthy Volunteers: No Sampling Method: Non-Probability Sample Criteria Inclusion Criteria: Clinical stage IB (>= 4 cm), II or IIIA non-squamous non-small cell lung cancer (NSCLC) Eastern Cooperative Oncology Group (ECOG) performance status 0-1 No patients who have received neoadjuvant therapy (chemo-…

Ages Eligible for Study: 18 Years and older   (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Previously registered to A151216 Central and/or local testing of EGFR with no EGFR exon 19 deletion or EGFR L858 R mutation Central and/or local testing of ALK with no ALK rearrangement…

Ages Eligible for Study: 18 Years and older   (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Histologically confirmed diagnosis of a solid tumor malignancy with KRAS G12C mutation Unresectable or metastatic disease Standard treatment is not available or patient declines Adequate organ function

Ages Eligible for Study: 18 Years and older   (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: STEP 1: SCREENING REGISTRATION Participants must have histologically or pathologically confirmed diagnosis of extensive stage small cell lung cancer (ES-SCLC) at the time of protocol entry Participants must have completed at…

Ages Eligible for Study: 18 Years and older   (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Patient must have pathologically confirmed non-squamous non-small cell lung carcinoma (NSCLC) Patient must have stage IV disease (includes M1a, M1b, or recurrent earlier stage disease), according to the 8th edition of…

Ages Eligible for Study: 18 Years and older   (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Pathologically (histologically or cytologically) proven diagnosis of limited stage small cell lung cancer (Stage Tx, T1-T4, N0-3, M0, American Joint Committee on Cancer [AJCC] staging, 8th edition [Ed.]), within 60 days…

Ages Eligible for Study: 18 Years and older   (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Patient must have a pathologically-confirmed diagnosis of non-squamous, non-small cell lung cancer (NSCLC) Patient must have advanced disease, defined as – either stage IV disease, stage IIIB disease not amenable to…

Ages Eligible for Study: 18 Years and older   (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Pathologically proven diagnosis of extensive stage small cell lung cancer Partial response (PR) or stable disease (SD) after 4-6 cycles of etoposide/platinum (E/P) doublet plus atezolizumab by re-staging scans (positron emission…